Remarkable Studies

Research Studies Demonstrate Improvements in Socialization, Mood, Focus, Behavior, and Brain Function

Rapid Results From Training Two Key Abilities

This new approach works far more quickly and effectively--requiring far fewer sessions to produce major improvements in autistic issues--than any of the others described in many journal articles since Dr. Cowan presented the first case of autism successfully treated with neurofeedback in 1994.  It is the only training system combining Neureka! and Focus.

The Socialize ACE™ trains the ability to Focus and sustain attention, and the ability to understand experiences (Neureka!) by putting together various types of perceptions, memories, and other information into a unified event. The individual with autistic issues, including Social Brain Dysfunction (SBD), lacks well developed and integrated systems to do this, the SBD sufferer has great difficulty making sense of their experience, and has problems learning appropriate behaviors.  

Improvements in Social Behavior and Clinical Scales

Our university-based collaborator, Dr. Sokhadze, gathered together the results from 18 sessions of training for all the clients he tested with the Social Responsiveness Scale-2 (SRS-2) in the published study and his more recent ongoing research.  The SRS-2 is considered to be one of the best and most complete scales. His findings included:

  • Normalization after training indicated by highly significant (p = .006) improvements in the total T score, a decrease from 83.5 to 71.0 in their parents' ratings, bringing the group average 51.0% closer to the normal score boundary of 59.  "p" is the probability this occurred by chance--called the significance level.  The smaller the better.
  • There was an even more significant improvement (p < .001) in the Social Communication subscale, also 51.0% of the way toward normal, and a 48.6% shift toward normal in Social Cognition (p < .01). The largest percentage shift toward normal was 79.2% for Motivation (p = .060).

Normalization of Social Responsiveness Scale-2 in 18 sessions

He found even larger improvements in attention deficit, and problems in depression, anxiety, attention and oppositional-defiant behavior for subjects tested with the the Achenbach System of Empirically Based Assessment (ASEBA), a comprehensive approach to assessing adaptive and maladaptive functioning with parent's ratings. These improvements actually brought them into the normal range.  That's why most of the percentages are actually more than 100%.

Normalization of ASEBA in 18 sessions

-Most values improved over the normal boundary.

Ithe previous, published study, there were significant improvements in both Lethargy/Social Withdrawal and Hyperactivity measured for the participants in the study on the Aberrant Behavior Checklist in 18 sessions. 

Dr. Sokhadze has also presented and published studies combining this neurofeedback technique with Transcranial Magnetic Stimulation (TMS), and found even stronger improvements.  Dr. Sokhadze presented this when he was given the Distinguished Scientist Award from the Association for Applied Psychophysiology and Biofeedback.  Unfortunately, TMS requires very expensive equipment and cannot be performed at home.

Very clearly, none of this occurred by chance, even with a small number of subjects.

Improvements in EEG

Four Brainwave Measures Improved Consistently

In the published study, the 18 children and adolescents with high functioning autism were trained for 18 sessions to improve their Focus measure and raise the Neureka! measure above a minimum, while keeping it below a maximum, which was hard to reach. There were quite significant improvements in both the Focus and Neureka! EEG measures, comparing the first and last session.  Increasing Neureka! made the experience enjoyable for the children, who were happy to participate.  There were no drop-outs.

As the graph shows, there was a very significant (p = .031) improvement in Neureka! (the graph titled “40 Hz. centered gamma”) across the sessions despite the fact that they weren't instructed to go all out to improve Neureka!, but just to keep it above a minimum.  That kept the movie going, and the better they did, the larger the picture they saw. This Neureka! measure showed clearer improvement over the 18 sessions than a traditionally filtered 40 Hz. band. This is consistent with it being easier to learn because it is not confounded with other gamma rhythms.

The Focused Attention measure was the most significantly (p = .001) improved by training.  While the article did not provide a graph for the Focused Attention measure, it did provide a graph for a more traditional measure of improvement in Attention in ADHD, the theta to low beta ratio, which was significantly (p = .046) improved during the study.  The graph shows that it was still decreasing at the end of the study. It was very highly correlated to the Focus measure. There were also very similar significant changes in the theta to high beta measure, and the overall theta to beta ratio, not shown here.

It's clear that all four measures were continuing to improve at the end of the 18 sessions, pointing to the idea that they could get even better with more sessions.  

Our proprietary customized measures were better than the more traditional ones, making our approach more effective and valuable than any competitor.  

Furthermore, the researchers found evidence that both of these changes (Focus and Neureka!) were related to the significant improvements in Lethargy/Social Withdrawal measured by the Aberrant Behavior Checklist.

 So as the brainwaves continue to improve with further training, the behavior should follow.   

Other Benefits of Neureka! And Focus Training

Another published study on more normal teenagers showed that the same combined training significantly:

  • ♦ Enhanced happiness ratings for at least four months.

  • ♦ Increased happiness during the training session, leading to better compliance with training.

  • ♦ Improved measures of attention.

  • ♦ Improved memory.

Although these have not yet been quantified in clients with Social Brain Dysfunction, the attention and memory improvements are consistent with the decreases in theta to beta ratios observed.

Comparison with Mente Autism Neurofeedback

  • ■ Takes a lot fewer sessions to show significant results (18 vs. 84).
    • ⚬Sessions are shorter:  30 vs 45 minutes.
    • ⚬Total training time for the studies of Socialize ACE™* was 14.2% of the Mente’s time.
  • ■ Socialize ACE™* showed highly significant improvements (51%) on the Social Responsiveness Scale - 2, while Mente showed no pre to post differences.
  • ■ Mente showed significantly worse scores on the Speech and Sensory/Cognitive Awareness scales of the Autism Treatment Evaluation Checklist after training.
  • ■ Mente's study started out with 200 participants and ended up with only 14, which were clearly not a representative sample.  Our studies have had no drop-outs.
  • ■ Socialize ACE™* trains both Focus and Neureka!, a brain system that integrates inputs and memories to understand events.  What Mente does to improve EEG is unclear, but it does not include the 40 cycle rhythm.

* Also part of the professional Peak BrainHappiness Trainer™.

Participate in an Ongoing Study

We are offering an opportunity for everyone who buys a Socialize ACE™ to participate in an ongoing study to monitor progress.  We will supply free testing on the Social Responsiveness Scale after every 9th session, which the parent will fill out online, and then provide you a graph of the client’s scores over time.

The purpose of this research is to see how individuals improve over sessions, taking this beyond the 18-24 sessions we have been able to employ in our research.

We are creating a website that will be initially open to client families and select professionals only.  It will anonymously chart and summarize this data, so that over time, we will be able to give participants a better idea of what to expect.  We will retain the rights to publicly release anonymous cumulative data, although formal publication will be limited because of the lack of IRB approval.